| Title |
Real-time Temperature Contol of High-temperature Chemotherapeutic Agents in HIPEC Surgery using a Smart Temperature Management System |
| DOI |
https://doi.org/10.5573/ieie.2025.62.8.95 |
| Keywords |
Hyperthermic intraperitoneal chemotherapy (HIPEC); Smart temperature management; Real-time temperature control; Cancer treatment; Automated temperature system |
| Abstract |
This study proposes a smart temperature management system capable of real-time control of temperature changes in the hyperthermic intraperitoneal chemotherapy (HIPEC) surgical treatment system, where high-temperature chemotherapy drugs are infused into the peritoneal cavity. HIPEC treatment involves the infusion of high-temperature chemotherapy drugs into the peritoneal cavity to induce necrosis of cancer tissues, thereby maximizing the therapeutic effect on the cancer. However, if the temperature deviates from the optimal therapeutic range of 41-43℃ during the infusion and drainage of the high-temperature drugs, it may reduce the treatment’s effectiveness and potentially cause heat damage to surrounding healthy tissues. The existing passive temperature control methods face challenges in managing temperature changes in real time during surgery. This paper designs a smart control system that detects the temperature of the drained drugs in real time using temperature sensors and maintains the optimal treatment temperature range of 41-43℃. The proposed system automatically adjusts functions such as heating, maintaining, cooling, and system shutdown based on temperature changes, ensuring stable maintenance of the therapeutic temperature. Through experiments, the proposed system was able to effectively maintain the temperature within the range of 41-43℃ for 120 minutes, achieving an accuracy of 99.88% and a margin of error of ±0.12%, demonstrating high performance. This study is expected to make a meaningful contribution to improving safety and efficiency in HIPEC surgical treatment through automated temperature control. |