| Title |
Use of Na+/K+ATPase in Maceobrachium nipponnese as a biomaker of lead pollution in aquatic ecosystem |
| Authors |
정명규 ( Myung Kiu Chung ) ; 김학희 ( Hak Hee Kim ) |
| Abstract |
Lead is one of the most toxic metal and is detectable in practically all phases of environment and in all biological system. Transport, industrial and domestic waste products are the main sources of this pollutant, Ingested lead is rapidly absorbed and widely distributed throughout the body, causing extensive tissue damage. In this study, we chose the freshwater decapods Maceobrachium nipponnese as a sensitive indicator organism for environmental pollution. In order to investigate the possibility in use of Na^+/L^+ ATPase activity as a biomarker of lead pollution. we tested the acute toxicity of lead to Maceobrachium nipponnese. The LC_50(96hr) value for lead in Maceobrachium nipponnese was found to be 446㎍/L with the 95% confidence limits. The lead exposure group at LC_50 showed a significant Na^+/K^+ATPase inhibition, depending on the exposure time. Comparision of several concentrations of lead revealed that the Na^+/K^+ATPase activity in Maceobrachium nipponnese was significantly decreased in a concentration dependent manner. These results suggest that Na^+/K^+ATPase activity in Maceobrachium nipponnese may possibly be used as a biomarker of lead pollution in aquatic ecosystem. |