| Keywords |
Obesity ; Metabolic syndrome ; GNB3 gene polymorphism ; Aerobic exercise ; Middle aged women |
| Abstract |
The purpose of this study was to investigate whether or not the GNB3 C825T gene polymorphism would modulate obesity and its metabolic syndrome markers responses to 12-week of aerobic exercise. Subjects of BMI>25 kg/m2 obesity middle aged women. Measured of body composition, blood pressures, blood lipids, blood glucose, insuin, HOMA-IR and GNB3 C825T gene polymorphism. Then all the participants underwent a 12-week (3 days/week) aerobic exercise. The GNB3 genotype was a significant modulator in determining some of the metabolic syndrome markers (i..e, TG (p=0.018), and HOMA-IR (p=0.033) responses to 12-week of aerobic exercise. The current findings of the study suggest that the GNB3 C825T gene polymorphism can partially be a genetic modulator of obesity and its related metabolic syndrome markers responses to exercise training in this study population. |