| Keywords |
Resistance exercise ; Hippocampus ; Acetylcholinesterase ; Acetylcholine ; Spatial memory |
| Abstract |
This study was performed to determine the effects of resistance exercise on Acetylcholinesterase (AChE) activity, concentration of Acetylcholine (ACh) and spatial memory as the escape latency in the Morris water maze testing. The rats were divided into two groups: control group without exercise and resistance exercise group. Rats in resistance exercise group performed training that climbed the ladder for 12 weeks. The statistical differences on the result were analyzed by independent t-test. The result showed that resistance exercise produced a significant decrease of AChE activity and increase of ACh concentration in hippocampus (p<.001). The spatial memory function which was measured by Morris water maze test was significantly enhanced in the resistance exercise group when compared with control group (p<.001). These data suggested that the decrease of AChE activity and increase of ACh may be involved in the enhancement of spatial memory function. |