| Keywords |
Aerobic capacity ; C-reactive protein(CRP) ; Ankle Brachial Index |
| Abstract |
The purpose of this study was to investigate the effect of aerobic capacity (VO2peak) would ameliorate inflammatory, anti-inflammatory markers and vascular function in patients with type 2 DM. To compare the importance of different inflammatory markers and traditional risk factors in predicting peripheral vascular disease(PAD) in patients with Type 2 diabetes mellitus. Diabetes mellitus (DM), chronic inflammation and vascular function are strongly related to increased cardiovascular risk. The purpose of this study was to evaluate whether an aerobic capacity (VO2peak) would ameliorate inflammatory, anti-inflammatory markers and vascular function in patients with type 2 DM. The subjects consisted 203 middle aged men who was aged 40-59 years were checked by blood test(including CRP), measurement of body fat, blood pressure, lipid profile, exercise stress testing and ABI. Aerobic capacity was determined in all individuals by measurement of maximal oxygen consumption during treadmill exercise. Control group VO2peak were significantly high compared with type 2 diabetes mellitus patients group(p=0.01). This study show that VO2peak levels are positively correlated with hsCRP (r=0.22) and ABI(ABI_R, r=0.137, ABI_L, r=0.86) in patient with type 2 diabetes mellitus. Higher physical conditioning status, indexed by VO2peak was associated with reduced arterial stiffness. The results of our study suggest that high aerobic exercise capacity was associated with reduced arterial stiffness in type 2 diabetes mellitus. |