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Title Effects of Voluntary Exercise on Energy Metabolism in Restraint Stress Induced Mice
Authors Myoung Uk Lee ; Yi Seul Kim ; Tae-Dong Kwon
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(Cover Date)
Vol.24 No.5(2017-10)
Keywords Voluntary exercise ; Restraint stress ; Energy metabolism
Abstract The purpose of this study is to observe the energy metabolism for voluntary exercise training effect after restraint stress in ICR mice. For this purpose, three different groups (21 ICR mouse were grouped as the control group CON, Restraint stress control group RSC, Restraint stress and Voluntary exercise RSV n=7) were used. The amounts of fat mass were decreased in RSV than CON and RSC(p<0.05). GLUT-2 protein expression increased in RSV in comparison with RSC (p<0.05). Akt protein expression increased in RSV in comparison with CON and RSC (p<0.05). AMPK protein expression was also increased in RSV compared with to CON and RSC(p<0.05). FNDC5 protein expression didn't show any significant differences between the groups. These results suggest that spontaneous exercise after stress induction can activate the signal pathway of energy metabolism and improve the exercise capacity.