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Title Changes in HDL-C Functionality and Cardiovascular Disease Risk Factors after Prolonged Exercise Training in Elderly Women with Low HDL-C
Authors Nayoung Ahn
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(Cover Date)
Vol.27 No.3(2020-06)
Keywords low HDL-C; exercise; elderly women; CVD; inflammatory factor
Abstract The purpose of this study is to analyze the effect of long-term exercise for the prevention of CVD in elderly women with low HDL-C levels on HDL-C levels, functional HDL-C and inflammatory factors. The subjects were divided into normal HDL-C group (≥50 mg/dL, Normal high density lipoprotein cholesterol: NHDL-C group, n=16) and low HDL-C group (<50 mg/dL, Low high density lipoprotein cholesterol: LHDL-C group, n=14) based on HDLC concentration in the elderly women over 65 years old. The aerobic and resistance exercise program consisted of a combination of silver dance and band exercise, 60 minutes a day, three times a week, and conducted at a medium intensity level for 24 weeks. As a result of the study, the LHDL-C group significantly (p<.05) increased plasma HDLC levels, APOA-1 and HSP70 levels. Physical fitness was significantly improved (p<.05) in both groups. The LHDLC group also significantly (p<.05) decreased IL-6 concentration and the risk of cardiovascular disease within 10 years.
Therefore, the long-term exercise program of the elderly women with low HDL-C level can have the effect of improving physical fitness, reducing inflammatory factors, improving qualitative HDL-C function, and cell regeneration mechanism.