https://doi.org/10.5370/KIEE.2026.75.1.174
이수연(Su-Yeon Lee) ; 윤종서(Jong-Seo Yoon) ; 이석희(Seok-Hui Lee) ; 이정은(Jung-Eun Lee) ; 이정환(Jeong-Whan Lee)
This study aims to verify the physiological validity and reliability of the cardiac dipole model by generating and analyzing 3-dimensional vectorcardiogram (VCG) signals based on the Frank Lead system.
First, we utilized ECG datasets from 30 healthy controls from the PTB Diagnostic ECG Database. The data was preprocessed to remove noise and baseline drift, and QRS peaks were detected to segment individual cardiac cycles. To minimize inter-individual variation, the signals were normalized based on the isoelectric PR segment. Using the normalized Frank Lead data (vx, vy, vz), a population-averaged VCG model was constructed. This model was then mapped onto a torso model that reflects Korean anatomical dimensions. We generated standard limb-leads (Lead I, II, III) by performing a vector projection between the VCG data and the RA, LA, and LL electrode positions. The correlation of these generated signals with measured ECG signals was then evaluated. The results showed a very high correlation for Lead I (r = 0.940) and Lead II (r = 0.823). This confirms that the proposed dipole model accurately reflects real cardiac electrical activity. In contrast, Lead III exhibited a lower correlation, which we attribute to inter-individual anatomical variability, such as rib position and torso length. In conclusion, this study demonstrates the reliability of the dipole-based VCG model, particularly for Leads I and II. The findings suggest that personalized modeling is necessary to improve the accuracy of Lead III. Furthermore, building on this validated dipole framework, the model can be extended to incorporate cardioid-based mathematical expressions to generate physiologically meaningful synthetic ECG signals for P, QRS, and T waves. This approach holds great potential for applications in cardiology simulations, algorithm development, and digital twin modeling.